<p>Body dissatisfaction among adolescent girls is a matter of concern considering its high prevalence, associated negative consequences, and impact on decreased psychological well-being which can lead to relational, work and social problems. This paper reports the findings of a study that used an A-B-A single-case research design to investigate the effect of dialectical behavioral therapy approach to improve psychological well-being in adolescents with body dissatisfaction. Participants consisted of three high school students (<i>N</i> = 3) who had negative body image and low psychological well-being category. Dialectical behavior therapy interventions were provided in 8 sessions. Treatment focuses on developing mindfulness skills, managing emotion regulation and interpersonal effectiveness skills. Self-report data were collected at pre-, during, and post-DBT timepoints. Visual analyzes revealed students who took part in dialectical behavior therapy experienced a significant reduction in body image dissatisfaction and increase in psychological well-being during and after three-weeks post-DBT. This evidence was suggested potential feasibility for using dialectical behavior therapy.</p><p>in increasing psychological well-being with adolescent body dissatisfaction.</p>