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<p>Potent Magnesium-Carbon Fullerene nanocomposite was created by a plasma reactor that vaporizes the Magnesium anode, and carbon cathode in the dielectric media (distilled water) by applying a powerful electric field between them. The Magnesium-Carbon Fullerene nanocomposite was characterized to examine its stability, shape, size, and crystal phase structure. Characterization analysis such as High Resolution Transmission Electron Microscope (HR-TEM), X-Ray Diffraction (XRD), Zeta potential, Fourier-transform infrared (FTIR), and Energy Dispersive X-ray (EDX) confirmed that the Synthesized Magnesium-Carbon Fullerene nanocomposite was successfully prepared with the nano with average polygonal Mg particle diameter 35 ± 5&#xa0;nm combined with carbon nano sheets with − 24.1 mv zetapotential indicating high stability. The 50% cell cytotoxic concentration equaled 201.85 ± 3.94&#xa0;µg/ml. The synthesized yield showed a potent antibacterial effect against the test microbes, reaching 150&#xa0;µg/ml minimum inhibitory concentration against <i>Staphylococcus aureus</i> while completely eradicating the bacterial growth after 20&#xa0;h of incubation. Moreover, Magnesium-Carbon Fullerene had a surprisingly high anti-inflammatory effect. Notably, Mg@C Fullerene nanocomposite demonstrated pronounced and specific inhibition of COX-2, with an IC<sub>50</sub> of 0.092 µM and a SI of 135.86.</p>

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Synthesized Mg@C Fullerene Nanocomposite Using a Plasma Reactor and its Biological Activity

  • 期刊论文

  • 发表日期：

    2025年6月14日

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  • Abeer Mogadem,
  • Awatif Rashed Z. Almotairy,
  • Mostafa El-Khatib,
  • Passant A. Ismail,
  • Bassma H. Elwakil

摘要

Potent Magnesium-Carbon Fullerene nanocomposite was created by a plasma reactor that vaporizes the Magnesium anode, and carbon cathode in the dielectric media (distilled water) by applying a powerful electric field between them. The Magnesium-Carbon Fullerene nanocomposite was characterized to examine its stability, shape, size, and crystal phase structure. Characterization analysis such as High Resolution Transmission Electron Microscope (HR-TEM), X-Ray Diffraction (XRD), Zeta potential, Fourier-transform infrared (FTIR), and Energy Dispersive X-ray (EDX) confirmed that the Synthesized Magnesium-Carbon Fullerene nanocomposite was successfully prepared with the nano with average polygonal Mg particle diameter 35 ± 5 nm combined with carbon nano sheets with − 24.1 mv zetapotential indicating high stability. The 50% cell cytotoxic concentration equaled 201.85 ± 3.94 µg/ml. The synthesized yield showed a potent antibacterial effect against the test microbes, reaching 150 µg/ml minimum inhibitory concentration against Staphylococcus aureus while completely eradicating the bacterial growth after 20 h of incubation. Moreover, Magnesium-Carbon Fullerene had a surprisingly high anti-inflammatory effect. Notably, Mg@C Fullerene nanocomposite demonstrated pronounced and specific inhibition of COX-2, with an IC50 of 0.092 µM and a SI of 135.86.