Scholarlink

<p>Coronary artery bypass grafting (CABG) via autologous vein or artery is still the gold standard surgery operative revascularization. However autologous vein/artery may represent some limitations like varicose veins or unavailability of veins due to reoperations especially in older patients. consequently, the research focus directed towards identification and characterization of biocompatible alternative material. Bacterial nanocellulose (BNC) as a natural material has gained substantial recognition in the research field of tissue engineering due to it exceptional attributes, including biocompatibility, enhanced mechanical properties, non-toxicity and unique physicochemical properties. Nevertheless, BNC is associated with some restrictions in endothelial cell adhesion and mimicking the physiochemical and mechanical properties of autologous vein as a promising alternative. To address these challenges, future research must focus on the development of BNC with controlled surface and mechanical characteristic. This review aims to address diverse aspect of controlling BNC production and methodologies in order to optimize the mechanical and physiochemical properties of grafts as an alternative in cardiovascular tissue engineering. Created with BioRender.com.</p><p></p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Bacterial nanocellulose: biosynthesis, structural properties and vascular tissue engineering applications

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年6月20日

查看全文
  • Saeed Sharifpoor Kermani,
  • Jens Wippermann,
  • Priya Veluswamy,
  • Max Wacker

摘要

Coronary artery bypass grafting (CABG) via autologous vein or artery is still the gold standard surgery operative revascularization. However autologous vein/artery may represent some limitations like varicose veins or unavailability of veins due to reoperations especially in older patients. consequently, the research focus directed towards identification and characterization of biocompatible alternative material. Bacterial nanocellulose (BNC) as a natural material has gained substantial recognition in the research field of tissue engineering due to it exceptional attributes, including biocompatibility, enhanced mechanical properties, non-toxicity and unique physicochemical properties. Nevertheless, BNC is associated with some restrictions in endothelial cell adhesion and mimicking the physiochemical and mechanical properties of autologous vein as a promising alternative. To address these challenges, future research must focus on the development of BNC with controlled surface and mechanical characteristic. This review aims to address diverse aspect of controlling BNC production and methodologies in order to optimize the mechanical and physiochemical properties of grafts as an alternative in cardiovascular tissue engineering. Created with BioRender.com.