<p>Purpose: Double-crown-retained dentures (DCRD) are an established treatment in dentistry. In some cases, the retention between primary crown (PC) and secondary crown (SC) loosens due to wear during daily handling of the denture. The aim of the present study was to examine modern materials for PCs and SCs with regard to their wear behavior. Materials and Methods: Cyclic pull-off tests were conducted on each 40 specimens in five test groups. PCs made of CoCr, PEEK and ZrO₂ were cemented onto a prepared resin tooth. SCs were made of the same materials and combined to the following PC-SC combinations: CoCr-CoCr, CoCr-PEEK, PEEK-PEEK, ZrO₂-PEEK, ZrO₂-ZrO₂. The wear areas on the contact surfaces between the PCs and the SCs were examined on SEM images. Results: Wear marks in form of scratches, chipping, ductile deformation or combinations of these forms were observed on the PCs and SCs in the various material combinations. The greatest wear on PCs was observed in the PEEK-PEEK group, while the greatest wear on SCs was observed in the ZrO₂-ZrO₂ group. The least wear was observed on SCs made of PEEK in combination with PCs made of ZrO₂. Conclusion: When using modern materials for DCRDs, the combination of different materials for PCs and SCs must be taken into account. The data found in this study show that only minor wear occurs at SCs made of PEEK, especially in combination with PCs made of ZrO₂. Therefore, this combination seems particularly suitable for increasing the longevity of DCRDs.</p> Graphical Abstract <p></p>