Scholarlink

<p>A nickel metal–organic framework (Ni-MOF)-based electrochemical sensor that is both straightforward and extremely sensitive has been created for the purpose of detecting acetaminophen. To validate its structural and morphological characteristics, the Ni-MOF composite was created and examined utilizing Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), scanning electron microscopy (SEM), and electrochemical methods. With an extraordinarily low detection limit of 0.243&#xa0;µM and a broad linear detection range of 0.8 to 400&#xa0;µM, the synthesized sensor demonstrated outstanding electrocatalytic activity toward acetaminophen oxidation. Through the measurement of acetaminophen in blood samples that had been tampered with, the analytical performance of the sensor was confirmed, and it achieved high recovery rates in comparison to conventional techniques. In addition, the sensor’s adaptability was demonstrated when it was effectively used for trace-level acetaminophen detection in blood samples. The Ni-MOF-modified electrode’s exceptional sensitivity, selectivity, and repeatability demonstrate its promise as a dependable and effective electrochemical platform for acetaminophen monitoring in biological and environmental samples.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Nickel-MOF electrochemical sensor: a high-performance platform for acetaminophen detection in blood samples

  • 期刊论文

  • 发表日期：

    2026年7月4日

查看全文
  • N. Sulochana,
  • B. P. Suma,
  • K. M. Supritha,
  • Shivayogeeswar Neelagund,
  • M. D. Gowtham,
  • M. Srinivas

摘要

A nickel metal–organic framework (Ni-MOF)-based electrochemical sensor that is both straightforward and extremely sensitive has been created for the purpose of detecting acetaminophen. To validate its structural and morphological characteristics, the Ni-MOF composite was created and examined utilizing Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), scanning electron microscopy (SEM), and electrochemical methods. With an extraordinarily low detection limit of 0.243 µM and a broad linear detection range of 0.8 to 400 µM, the synthesized sensor demonstrated outstanding electrocatalytic activity toward acetaminophen oxidation. Through the measurement of acetaminophen in blood samples that had been tampered with, the analytical performance of the sensor was confirmed, and it achieved high recovery rates in comparison to conventional techniques. In addition, the sensor’s adaptability was demonstrated when it was effectively used for trace-level acetaminophen detection in blood samples. The Ni-MOF-modified electrode’s exceptional sensitivity, selectivity, and repeatability demonstrate its promise as a dependable and effective electrochemical platform for acetaminophen monitoring in biological and environmental samples.