<p>A novel nonenzymatic electrochemical glucose sensor based on a palladium nanoparticle-decorated zinc oxide nanorod nanocomposite, which was synthesized through a facile hydrothermal approach, was developed in this study. The morphological and structural features of the nanocomposite were comprehensively examined by using field-emission scanning electron microscopy, energy-dispersive X-ray spectroscopy, X-ray diffraction, and UV–Vis spectroscopy. Moreover, the electrochemical performance of the nanocomposite was systematically evaluated through cyclic voltammetry (CV) and chronoamperometry (CA). The fabricated glucose sensor exhibited high sensitivity, low detection limits, and values of 27.12 μA mM<sup>−1</sup>&#xa0;cm<sup>−2</sup>, 1.39 × 10<sup>−5</sup>&#xa0;mM, and 0.1–10.0&#xa0;mM in CV, respectively, and 14.31 μA mM<sup>−1</sup>&#xa0;cm<sup>−2</sup>, 2.65 × 10<sup>−5</sup>&#xa0;mM, and 0.5–15.0&#xa0;mM in CA, respectively. Furthermore, it displayed excellent selectivity against common interfering species, along with high reproducibility (relative standard deviation [RSD] = 3.02%) and repeatability (RSD = 1.75%) while retaining 94.5% of its initial response after 30&#xa0;days. Collectively, these findings highlight the potential of the proposed sensor as a robust, cost-effective, and stable platform for real-time nonenzymatic glucose detection and quantification in biomedical applications.</p>

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Schottky junction-mediated nonenzymatic glucose sensing using Pd nanoparticle-decorated ZnO nanorods

  • Ngo Thi Quyen,
  • Manh Trung Tran,
  • Phuong Dinh Tam

摘要

A novel nonenzymatic electrochemical glucose sensor based on a palladium nanoparticle-decorated zinc oxide nanorod nanocomposite, which was synthesized through a facile hydrothermal approach, was developed in this study. The morphological and structural features of the nanocomposite were comprehensively examined by using field-emission scanning electron microscopy, energy-dispersive X-ray spectroscopy, X-ray diffraction, and UV–Vis spectroscopy. Moreover, the electrochemical performance of the nanocomposite was systematically evaluated through cyclic voltammetry (CV) and chronoamperometry (CA). The fabricated glucose sensor exhibited high sensitivity, low detection limits, and values of 27.12 μA mM−1 cm−2, 1.39 × 10−5 mM, and 0.1–10.0 mM in CV, respectively, and 14.31 μA mM−1 cm−2, 2.65 × 10−5 mM, and 0.5–15.0 mM in CA, respectively. Furthermore, it displayed excellent selectivity against common interfering species, along with high reproducibility (relative standard deviation [RSD] = 3.02%) and repeatability (RSD = 1.75%) while retaining 94.5% of its initial response after 30 days. Collectively, these findings highlight the potential of the proposed sensor as a robust, cost-effective, and stable platform for real-time nonenzymatic glucose detection and quantification in biomedical applications.