<p>A bactericide known as triclosan (TC) has recently been identified as a pollutant that can disrupt the endocrine system and harmful towards the aquatic life. The primary focus of research today is determination of TC in biochemical, environmental, and pneumocystis pneumonia (PCP) samples by facile and cost-effective method. In this work, our study reported that novel free-standing electrochemical sensor for ultrasensitive and discriminatory non-enzymatic detection of triclosan using zinc metal organic framework (MOF) anchored graphite rod. Succulent-like Zn(BPDA)MOFs were synthesized via an easy, simplistic one-step hydrothermal method. Inter-connected Zn(BPDA)MOFs sheets deliver large exterior area, enormous pore amount and abundant reactive spots, which may enhance electrocatalytic efficacy towards TC. The MOFs anchored graphite rod electrode demonstrated own excellent electrochemical attributes, and electronic conductivity, which could endorse the electro-oxidation towards the adsorbed triclosan. The sensor electrode showed a wide linear region from 0.25 to 350&#xa0;µM, limit of detection (LOD) of 1.8&#xa0;nM and high sensitivity value of 76.80 μA μM⁻¹&#xa0;cm⁻², using differential pulse voltammetry (DPV) under optimized conditions. Moreover, Zn(BPDA)MOF/GR electrode showed an unique discrimination performance and excellent duplicability, outstanding repeatability, and brilliant storing steadiness up to one months. The proposed electrode was efficaciously applied for the determination of triclosan in spiked mouthwash and sanitizer samples with acceptable recovery results. Therefore, the sensor electrode provides simple, affordable, environment friendly, portable and cost-effective TC detection tool.</p>