<p>The study investigates the common issue of prosthetic abutment screw loosening in implant dentistry, which is often caused by microgaps at the implant–abutment interface. Packing agents are typically used to mitigate microleakage. The research specifically examines the role of collagen doped with diamond-like carbon (HDLCC) nanofilms as packing gel, which could provide high wear resistance and reduced friction. However, their effectiveness and influence on the mechanical behavior of implant systems remain uncertain. The study analyzed three implant models, Nobel (NL), Straumann, (STRM), and WEGO (WO), with and without HDLCC coatings. The plasma-enhanced chemical vapor deposition method was employed to coat HDLCC nanofilm on the surface of the abutment screw. The study aimed to assess the effects of HDLCC coating on thread wear, torque loss of abutment screws, and microleakage within a simulated oral environment, involving a total of 30 samples. After subjecting abutments to a 30⁰ off-axis dynamic force of 20 to 200 N for 48&#xa0;h, scanning electron microscopy and a ball-on-flat setup were used to evaluate morphologies and gel friction. Statistical analysis indicated that HDLCC coating reduced microleakage and increased optical density, particularly in STRM implants after 12&#xa0;h of cyclic loading (<i>P</i> = 0.44). Moreover, torque loss was observed during tightening and increased under dynamic load across all groups, with STRM implants exhibiting the best antiloosening property (<i>P</i> &lt; .001). The application of HDLCC gel decreased both initial (<i>P</i> = .048) and final torque loss rates (<i>P</i> = .032) in all systems.</p>