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<p>The growing threat of antimicrobial resistance has driven the search for innovative infection-control materials. Bioactive antimicrobial polymeric membranes (BAPMs) have gained attention for their multifunctionality, biocompatibility, and tunable properties. This review summarizes recent progress in the synthesis, characterization, and applications of BAPMs. Fabrication techniques such as electrospinning, phase separation, and chemical grafting are discussed, emphasizing their effects on membrane morphology and antimicrobial efficiency. The incorporation of bioactive agents, including natural compounds, nanoparticles, and synthetic antimicrobials, is explored for enhancing membrane performance. Key characterization tools like scanning electron microscopy (SEM), Fourier-transform infrared spectroscopy (FTIR), and mechanical testing are reviewed for assessing structure and function. BAPMs demonstrate broad applications in wound healing, tissue engineering, water purification, and food packaging. In biomedical fields, they provide localized and sustained antimicrobial activity, promoting wound recovery and infection prevention. Environmentally, they offer sustainable solutions against waterborne pathogens. The review also highlights emerging trends, including stimuli-responsive polymers and advanced synthesis strategies, guiding future research toward next-generation antimicrobial membranes with superior performance and sustainability.</p> Graphical abstract <p></p>

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Bioactive antimicrobial polymer membranes: synthesis, characterization, and their applications in various sectors

  • 期刊论文

  • 发表日期：

    2025年12月9日

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  • Thi Tuong Vy Phan,
  • Madhappan Santhamoorthy,
  • Kokila Thirupathi,
  • Mei-Ching Lin,
  • Seong-Cheol Kim,
  • Keerthika Kumarasamy

摘要

The growing threat of antimicrobial resistance has driven the search for innovative infection-control materials. Bioactive antimicrobial polymeric membranes (BAPMs) have gained attention for their multifunctionality, biocompatibility, and tunable properties. This review summarizes recent progress in the synthesis, characterization, and applications of BAPMs. Fabrication techniques such as electrospinning, phase separation, and chemical grafting are discussed, emphasizing their effects on membrane morphology and antimicrobial efficiency. The incorporation of bioactive agents, including natural compounds, nanoparticles, and synthetic antimicrobials, is explored for enhancing membrane performance. Key characterization tools like scanning electron microscopy (SEM), Fourier-transform infrared spectroscopy (FTIR), and mechanical testing are reviewed for assessing structure and function. BAPMs demonstrate broad applications in wound healing, tissue engineering, water purification, and food packaging. In biomedical fields, they provide localized and sustained antimicrobial activity, promoting wound recovery and infection prevention. Environmentally, they offer sustainable solutions against waterborne pathogens. The review also highlights emerging trends, including stimuli-responsive polymers and advanced synthesis strategies, guiding future research toward next-generation antimicrobial membranes with superior performance and sustainability.

Graphical abstract