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<p>The study focuses on an 8-week dyadic mindfulness-based intervention programme aimed at decreasing unpleasant or upsetting emotions in both caregivers and children and improving the caregiver-child relationship in children with leukemia and their caregivers. Seventy child-caregiver dyads were randomly allocated to either the mindfulness intervention group (<i>n</i> = 35) or a control group (<i>n</i> = 35). Outcome measures assessing negative emotional states and relationship quality were administered at baseline, post-intervention, and 1-month follow-up. The data were analyzed using generalized estimating equations (GEE), which revealed significant group×time interaction effects for children’s emotional symptoms (Wald χ²=13.07, <i>p</i> = 0.001), caregivers’ depressive symptoms (Wald χ²=27.74, <i>p</i> &lt; 0.001), caregivers’ stress levels (Wald χ²=13.55, <i>p</i> = 0.001), and caregiver-child relationship quality (Wald χ²=6.85, <i>p</i> = 0.032). However, no significant intervention effect was observed for anxiety symptoms. These findings provide preliminary evidence supporting the beneficial effects of this dyadic mindfulness-based intervention for improving psychological outcomes in pediatric leukemia patients and their family caregivers.</p>

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Effect of Dyadic Mindfulness-Based Intervention Program on Children with Leukemia and Their Caregivers

  • 期刊论文

  • 发表日期：

    2026年6月22日

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  • Mingyu Chang,
  • Siyu Wang,
  • Mengjia Wang,
  • Ruixing Zhang

摘要

The study focuses on an 8-week dyadic mindfulness-based intervention programme aimed at decreasing unpleasant or upsetting emotions in both caregivers and children and improving the caregiver-child relationship in children with leukemia and their caregivers. Seventy child-caregiver dyads were randomly allocated to either the mindfulness intervention group (n = 35) or a control group (n = 35). Outcome measures assessing negative emotional states and relationship quality were administered at baseline, post-intervention, and 1-month follow-up. The data were analyzed using generalized estimating equations (GEE), which revealed significant group×time interaction effects for children’s emotional symptoms (Wald χ²=13.07, p = 0.001), caregivers’ depressive symptoms (Wald χ²=27.74, p < 0.001), caregivers’ stress levels (Wald χ²=13.55, p = 0.001), and caregiver-child relationship quality (Wald χ²=6.85, p = 0.032). However, no significant intervention effect was observed for anxiety symptoms. These findings provide preliminary evidence supporting the beneficial effects of this dyadic mindfulness-based intervention for improving psychological outcomes in pediatric leukemia patients and their family caregivers.