Scholarlink

Purpose <p>Meibomian gland dysfunction (MGD) is a leading cause of evaporative dry eye disease (DED), and its exacerbation after cataract surgery has been reported. This study aims to evaluate meibomian gland (MG) morphological and functional changes following cataract surgery and identify influencing factors.</p> Methods <p>This prospective, observational study included 132 patients who underwent phacoemulsification with intraocular lens implantation. Meibomian gland loss (MGL) and non-invasive tear break-up time (NI-BUT) were assessed preoperatively at postoperative week one, and at month one using a corneal topography device via infrared meibography (Sirius, CSO, Italy). Correlations between MGL, NI-BUT, cataract grade, and surgery duration were analyzed.</p> Results <p>Postoperatively, MGL increased at week one (32.0% ± 15.1) and month one (30.9% ± 14.5) compared to preoperative values (15.1% ± 7.0). NI-BUT decreased at both time points (week one: 6.8&#xa0;s ± 4.3; month one: 6.7&#xa0;s ± 4.6; preoperative: 9.4&#xa0;s ± 4.5). A significant correlation was found between increased MGL and longer surgery duration (<i>p</i> &lt; 0.001). ROC analysis identified a surgical duration threshold of 11.5&#xa0;min, beyond which MGL changes were more pronounced.</p> Conclusions <p>Cataract surgery induces significant MG changes, with increased MGL and reduced NI-BUT postoperatively. Longer surgical duration is a key risk factor for MG deterioration. These findings highlight the importance of ocular surface management in cataract surgery to improve postoperative outcomes.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Meibomian gland changes and influencing factors following cataract surgery

  • 期刊论文

  • 发表日期：

    2025年11月17日

查看全文
  • Fuat Yavrum,
  • Berra Alcıkaya,
  • Ayşegül Acar,
  • Nedime Şahinoğlu-Keşkek

摘要

Purpose

Meibomian gland dysfunction (MGD) is a leading cause of evaporative dry eye disease (DED), and its exacerbation after cataract surgery has been reported. This study aims to evaluate meibomian gland (MG) morphological and functional changes following cataract surgery and identify influencing factors.

Methods

This prospective, observational study included 132 patients who underwent phacoemulsification with intraocular lens implantation. Meibomian gland loss (MGL) and non-invasive tear break-up time (NI-BUT) were assessed preoperatively at postoperative week one, and at month one using a corneal topography device via infrared meibography (Sirius, CSO, Italy). Correlations between MGL, NI-BUT, cataract grade, and surgery duration were analyzed.

Results

Postoperatively, MGL increased at week one (32.0% ± 15.1) and month one (30.9% ± 14.5) compared to preoperative values (15.1% ± 7.0). NI-BUT decreased at both time points (week one: 6.8 s ± 4.3; month one: 6.7 s ± 4.6; preoperative: 9.4 s ± 4.5). A significant correlation was found between increased MGL and longer surgery duration (p < 0.001). ROC analysis identified a surgical duration threshold of 11.5 min, beyond which MGL changes were more pronounced.

Conclusions

Cataract surgery induces significant MG changes, with increased MGL and reduced NI-BUT postoperatively. Longer surgical duration is a key risk factor for MG deterioration. These findings highlight the importance of ocular surface management in cataract surgery to improve postoperative outcomes.