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<p>We have developed an approximate hydromechanical method that enables cardiologists to quantitatively assess alterations in the dynamic characteristics of the blood flow in the larger coronary arteries which result from pathological tortuosity, and to determine the hemodynamic significance of these changes using data obtained exclusively from the coronary angiography. Application of this method to relevant patient cases has demonstrated that the hemodynamic significance of tortuosity increases or decreases proportionally to its hemodynamic resistance. Critical threshold values have been identified for the number of angulations, the relative blood flow loss, and the frequency of angina attacks beyond which the corresponding tortuosity becomes hemodynamically significant. Furthermore, strong correlation has been established between key characteristics of tortuosity and principal clinical indicators in patients.</p>

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Approximate Method to Find Dynamic Blood Flow Characteristics in Pathologically Tortuous Larger Coronary Artery

  • 期刊论文

  • 发表日期：

    2025年5月1日

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  • A. O. Borysyuk

摘要

We have developed an approximate hydromechanical method that enables cardiologists to quantitatively assess alterations in the dynamic characteristics of the blood flow in the larger coronary arteries which result from pathological tortuosity, and to determine the hemodynamic significance of these changes using data obtained exclusively from the coronary angiography. Application of this method to relevant patient cases has demonstrated that the hemodynamic significance of tortuosity increases or decreases proportionally to its hemodynamic resistance. Critical threshold values have been identified for the number of angulations, the relative blood flow loss, and the frequency of angina attacks beyond which the corresponding tortuosity becomes hemodynamically significant. Furthermore, strong correlation has been established between key characteristics of tortuosity and principal clinical indicators in patients.