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<p>The antibacterial activity is tested against gram positive and gram negative bacterium. The bio-synthesis approach has recently gained significant attention due to its potential to offer safer, more efficient, and environmentally friendly alternatives for nanoparticle production. This method emphasizes the responsible use of various materials during synthesis. The present study focuses on the green synthesis of pure and Copper doped titanium dioxide (TiO<sub>2</sub>) nanoparticles using <i>Aloe barbadensis miller</i> leaf extract. The synthesized nanoparticles were analyzed using techniques such as X-ray Diffraction (XRD), Scanning Electron Microscopy (SEM), and Energy Dispersive X-ray Spectroscopy (EDX) to determine their average crystallite size, particle size, morphology, and structural properties. The findings verified that the TiO<sub>2</sub> nanoparticles exhibit a tetragonal crystal structure characteristic of the anatase phase. Their antibacterial efficacy was evaluated against both gram-positive <i>Staphylococcus aureus</i> and gram-negative <i>Escherichia coli</i> bacteria which proved excellent results.</p>

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Synthesis of undoped and doped titanium di-oxide (TIO2) nanoparticles to study their antibacterial activity

  • 期刊论文

  • 发表日期：

    2025年8月29日

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  • Prathamesh S. Wagh,
  • Gajanan T. Lamdhade,
  • Kishor B. Raulkar

摘要

The antibacterial activity is tested against gram positive and gram negative bacterium. The bio-synthesis approach has recently gained significant attention due to its potential to offer safer, more efficient, and environmentally friendly alternatives for nanoparticle production. This method emphasizes the responsible use of various materials during synthesis. The present study focuses on the green synthesis of pure and Copper doped titanium dioxide (TiO2) nanoparticles using Aloe barbadensis miller leaf extract. The synthesized nanoparticles were analyzed using techniques such as X-ray Diffraction (XRD), Scanning Electron Microscopy (SEM), and Energy Dispersive X-ray Spectroscopy (EDX) to determine their average crystallite size, particle size, morphology, and structural properties. The findings verified that the TiO2 nanoparticles exhibit a tetragonal crystal structure characteristic of the anatase phase. Their antibacterial efficacy was evaluated against both gram-positive Staphylococcus aureus and gram-negative Escherichia coli bacteria which proved excellent results.