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<p>Renal Denervation (RDN) has emerged over the last decade as a third pillar in the treatment of arterial hypertension, alongside pharmacotherapy and lifestyle modifications. Mechanistically, it reduces central sympathetic overactivation, a process also relevant to heart failure. In this mini-review, we summarize the development of RDN for heart failure, discuss the current evidence supporting its effects, and provide an outlook on future developments.</p>

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Renal denervation in the setting of heart failure

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年1月29日

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  • Franziska Koppe-Schmeißer,
  • Karl Fengler,
  • Karl-Patrik Kresoja,
  • Philipp Lurz,
  • Karl-Philipp Rommel

摘要

Renal Denervation (RDN) has emerged over the last decade as a third pillar in the treatment of arterial hypertension, alongside pharmacotherapy and lifestyle modifications. Mechanistically, it reduces central sympathetic overactivation, a process also relevant to heart failure. In this mini-review, we summarize the development of RDN for heart failure, discuss the current evidence supporting its effects, and provide an outlook on future developments.