The Positive Influence Dominating Set Problem (PIDS) is a variant of the well-known Dominating Set Problem. It involves selecting a subset of vertices that positively dominate the remaining vertices in a given graph \(G=(V,E)\) . More formally, a vertex \(v_i \in V\) is said to be positively dominated if at least a portion of \(\rho deg_G(v_i)\) of its neighbors belongs to the selected set, where \(deg_G(v_i)\) is the degree of \(v_i\) , and \(0<\rho <1\) is the influence factor. The objective is to identify the smallest subset of positive influence dominants. This problem is NP-hard on general graphs and remains computationally challenging even for particular classes of graphs. In this paper, we propose an efficient algorithm for solving PIDS, based on the Local Branching approach combined with the CPLEX mathematical programming solver, especially to enhance intensification and provide a good partial solution. Also, to ensure solution diversification, we develop a destructive-reconstructive greedy heuristic to explore previously unvisited subspaces. We conduct extensive experiments to evaluate our method on real-world benchmark instances of varying sizes, including large-scale graphs, and compare it with five existing state-of-the-art solving approaches. The experimental results demonstrate that the proposed approach yields high-quality solutions within reasonable computational times, highlighting its performance for efficiently solving PIDS.