<p>Trauma centers (TCs) play a crucial role in improving patient safety of severely injured individuals, but require substantial financial resources to operate effectively. TCs in low-insured areas are particularly at risk of being confronted with financial deficits, and a threat of closure, due to the inability to recover costs from uncompensated care. While some states in the US provide financial subsidies to support these centers, the diversity of state subsidy policies and their impacts on TC financial viability are poorly understood. To address this, we introduce a generalized subsidy distribution formula that incorporates key components from various state policies. Based on that, we further propose a TC Financial Evaluation Model that employs Monte Carlo simulation to assess the effects of different subsidy policies along three proposed metrics. Utilizing realistic data from multiple US states and national insurance statistics, we conduct a comprehensive experimental study. Our findings suggest that the financial performance of TCs could be affected by the total subsidy amount, the Uninsured level within the Trauma Service Area (TSA), and the specific subsidy distribution policy employed. This research provides trauma decision-makers a quantitative tool to evaluate, compare, and design subsidy policies tailored to their unique demographic and economic contexts, potentially leading to a more standardized approach to mitigate existing policy disparities across states.</p>