<p>Senescence is a complex, tightly regulated developmental process that culminates in programmed cell death. Flowers serve as ideal model systems for senescence studies due to their relatively homogeneous tissues, which facilitate the application of chemical treatments with minimal tissue damage. Floral senescence is triggered by various intrinsic and environmental factors and is orchestrated by plant growth regulators, particularly ethylene, which plays a central role in regulating petal senescence. Molecular studies have led to the identification and characterization of numerous genes involved in the regulation of this complex process. However, despite significant advances, the underlying mechanisms governing floral senescence remain incompletely understood, necessitating further focused research using diverse flower systems.A deeper understanding of flower senescence, particularly in ornamental species, holds potential for the development of strategies to prolong vase life through modern biotechnological approaches. One such promising approach is the use of the clustered regularly interspaced short palindromic repeat (CRISPR)-associated protein 9 (Cas9) system - a powerful tool for targeted gene editing across a wide range of organisms, including plants. The precision offered by CRISPR-Cas9 enables the manipulation of specific genes associated with aging and senescence. For instance, targeted knockout of genes involved in ethylene perception and signalling has been shown to delay petal senescence and significantly extend flower longevity.Recent studies have demonstrated the utility of CRISPR-Cas9 technology in manipulating floral traits, offering valuable prospects for improving ornamental value and optimizing crop productivity. This review aims to summarize the current state of research on gene editing approaches to understand and manipulate floral senescence in ornamental plants, and to highlight the future potential of CRISPRbased technologies in advancing floriculture.</p>