<p>In this study we evaluated the wayfinding performance and use of tactile maps and mobile apps by twenty-eight visually impaired adolescents and adults. Employing a repeated-measures, within-subjects design for the wayfinding modality comparison, participants navigated two unfamiliar pedestrian routes, each comprised of indoor and outdoor segments. Participants completed one route using tactile maps and the second route using a combination of contemporary navigation apps that provided turn-by-turn instructions. Our research specifically investigated how wayfinding modalities and between-subject factors, such as participants’ age and visual function group, impact wayfinding performance. Quantitative analysis of route completion times revealed that mobile apps were more effective for outdoor navigation than tactile maps, though no significant difference was found for indoor segments. In addition, participants with higher visual function completed routes significantly faster regardless of the modality. Furthermore, adolescents performed faster than adults with tactile maps outdoors. Qualitative data from focus groups further elucidated user experiences, challenges during indoor/outdoor transitions, and the importance of auditory feedback and detailed environmental information. Our findings highlight the need for user-centered wayfinding apps that support seamless indoor and outdoor navigation, alongside the continued importance of orientation and mobility instruction to enhance independence, safety, and confidence for visually impaired individuals.</p>