<p>This study involved porosity–permeability and effective stress-permeability measurements under hydrostatic conditions to analyze the exponents α (permeability–porosity sensitivity coefficient) and γ (stress sensitivity coefficient) in artificial sandstones. Using a steady-state method, permeability tests were conducted on samples with varying particle size distributions and cement contents. The results showed that before pore collapse, permeability-stress and permeability–porosity relations adhered to established models. For samples with the same particle size distribution, a linear relationship was observed between cement content and stress sensitivity. The permeability–porosity sensitivity coefficient increased nonlinearly with solid volume compaction. Higher initial porosity and permeability reduced sensitivity to stress and porosity. Increased effective stress consistently reduced porosity and permeability, followed by a decrease in sensitivity coefficients. Samples with lower cement content showed reduced stress sensitivity due to larger pore throats. At critical stress levels, permeability sharply decreased by an order of magnitude, with a concurrent reduction in sensitivity coefficients. This behavior is influenced by pore collapse, debris clogging, and potential new fluid pathways created by grain-level cracking. These findings highlight the complex interplay between mechanical properties and permeability in engineered and natural sandstone systems.</p>