<p>Floods, whether natural or anthropogenic, result in significant loss of life, property damage, and disruption to social and economic stability. The Teesta River basin in India, a flood-prone region, has experienced numerous historical flood events. This study comprehensively assessed the flood risk in the lower Teesta River basin by integrating flood hazard and vulnerability analyses. Flood hazard assessment of a specific flood event of 2016 was accomplished with the Hydrologic Engineering Centre – River Analysis System 2D (HEC-RAS 2D) model furnishing information such as inundation extent, water surface elevation, velocity, and flood depth. Invoking experts’opinion, seventeen flood-causative factors categorized under five major criteria namely, morphological, land use and soil, hydrological, exposed elements, and socio-economic were integrated by analytic hierarchy process (AHP) to prepare the flood vulnerability map which was classified into five vulnerable zones. The area under curve (AUC) values of 0.927 and 0.782 for flood hazard and vulnerability maps respectively, suggested that the generated maps were reliable. Finally, the hazard and vulnerability maps were integrated to generate the flood risk map, revealing that most of the inundated areas of different blocks were classified under “high” flood risk zones. This finding was substantiated by a synthetic aperture radar (SAR) image of the flood event which marked the traces of flood water in the high-risk areas. This integrated approach provides a robust framework for understanding flood dynamics and offers actionable insights for sustainable flood management and mitigation strategies. It also enhances community resilience promoting sustainable development in flood-prone regions.</p>