Accumulation of antibiotics in groundwater of the damodar river basin, India and health risk prediction: source identification and linkage with hydrochemistry
摘要
Monitoring of antibiotics in groundwater, their transport mechanism, and associated health and ecological risks draws serious attention of the global scientific community nowadays. The present article is the first report of the detection of 12 antibiotics in the groundwater of the Damodar river basin in India using Ultra High Performance Liquid Chromatography-High Resolution Mass Spectrometry after analysing 749 samples collected during three different seasons in 49 locations. The sum of the total concentrations of erythromycin (646.08 ng/L), sulfadiazine (323.76 ng/L), and doxycycline (547.81 ng/L) is found to be high. Detrended correspondence analysis and redundancy analysis studies reveal a long-term sustainability of antibiotics in the groundwater due to their interaction with geochemical variables. The investigation of the transport drivers demonstrates that the study area’s soil type, soil pH (5.49–6.11), and groundwater pH (6.71–8.85) dominate the targeted antibiotic migration process. Monte Carlo Simulation study reveals that erythromycin, clarithromycin, doxycycline, sulfadiazine, and sulfamethoxazole are the foremost antibiotics contributing to human health hazards and ecological risks. Sarafloxacin shows a higher health impact on children than adults. On the other hand, clarithromycin, ciprofloxacin, and erythromycin provide significant ecological risks to the algae species of the basin. The source apportionment approach and principal component analysis explore that these antibiotics may originate from one or more of the sources: (a) untreated domestic sewage, (b) hospital discharges, (c) industrial effluents, and (d) livestock waste. The prepared spatial distribution maps show that the Asansol-Durgapur industrial regions are the most polluted zones in the entire basin.
Graphical Abstract