<p>Changes in turbidity have strong effects on biodiversity and functioning in freshwater ecosystems. However, little is known about its effects on the strength of predator–prey interactions involving invasive fish species. In this study, we conducted mesocosm experiments to evaluate the effects of organic turbidity on predator–prey interactions between the yellow peacock bass (<i>Cichla kelberi</i>, visual predator) and Nile tilapia (<i>Oreochromis niloticus,</i> prey), two highly invasive fish widely introduced across the globe. We investigated the hypothesis that increased turbidity reduces the feeding rates and prey size selection of the predator, favoring prey survival. We found very strong evidence that water turbidity affected total consumption of the peacock bass, with a non-linear response along the turbidity gradient: consumption rates in the low turbid level (~ 25 NTU) were higher than in the control (0 NTU), intermediate (~ 50 NTU) and high turbidity levels (~ 100 NTU). Moreover, peacock basses showed a non-random feeding preference towards small tilapia in clear and low turbidity levels, but random preference in intermediate and high levels. Our results demonstrate that variations in turbidity modulate the strength of predator–prey interactions, constraining consumption rates and prey size selection by the peacock bass, consequently favoring tilapia survival. These findings provide evidence that increasing turbidity may differentially influence the invasion success and ecological impact of non-native predator and prey.</p>