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Background <p><i>Candida</i> overgrowth in the small intestine can cause non-specific gastrointestinal symptoms mimicking those of other conditions, making diagnosis challenging.</p> Aims <p>To describe the characteristics of patients with <i>Candida</i>-related intestinal illness in a large US commercial health insurance claims dataset.</p> Methods <p>We used the Merative™ MarketScan® Commercial/Medicare Database to identify patients who received <i>Candida</i> enteritis diagnosis codes.</p> Results <p>We identified 3,710 patients. Rates were higher among women (20.3/100,000), patients ages 35–44 (19.3/100,000) and in the West (28.1/100,000). Fatigue (44%) and abdominal pain (26%) were common symptoms. Few patients (6%) received an esophagogastroduodenoscopy, the preferred diagnostic method, and 38% received systemic antifungal therapy.</p> Conclusions <p>Increased healthcare provider awareness about proper diagnosis and treatment of intestinal <i>Candida</i> overgrowth could be beneficial.</p>

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Candida Enteritis Diagnoses in the United States: Prevalence and Clinical Insights from a Large Commercial Insurance Database

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年4月16日

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  • Kaitlin Benedict,
  • Jeremy A. W. Gold,
  • Mark Pimentel

摘要

Background

Candida overgrowth in the small intestine can cause non-specific gastrointestinal symptoms mimicking those of other conditions, making diagnosis challenging.

Aims

To describe the characteristics of patients with Candida-related intestinal illness in a large US commercial health insurance claims dataset.

Methods

We used the Merative™ MarketScan® Commercial/Medicare Database to identify patients who received Candida enteritis diagnosis codes.

Results

We identified 3,710 patients. Rates were higher among women (20.3/100,000), patients ages 35–44 (19.3/100,000) and in the West (28.1/100,000). Fatigue (44%) and abdominal pain (26%) were common symptoms. Few patients (6%) received an esophagogastroduodenoscopy, the preferred diagnostic method, and 38% received systemic antifungal therapy.

Conclusions

Increased healthcare provider awareness about proper diagnosis and treatment of intestinal Candida overgrowth could be beneficial.