Scholarlink

Background <p>There is lack of direct comparison between different endoscopic ultrasound (EUS)-guided fine-needle biopsy (FNB) needles for tissue sampling of subepithelial lesions (SELs).</p> Aims <p>We aimed to compare Franseen vs forward bevel needle in patients with SELs.</p> Methods <p>Out of 483 patients undergoing endoscopic sampling of SELs, after propensity score matching two groups were compared: 145 undergoing EUS-FNB with 22G Franseen and 145 with 20G forward bevel needle. The primary outcome was diagnostic accuracy. Secondary outcomes were sample adequacy, quality of the sample, sensitivity, specificity, and adverse event rate.</p> Results <p>Sample adequacy and diagnostic accuracy rates were significantly higher with the Franseen needle (98.6 vs 89.6% and 96.5 vs 88.9%; <i>p</i> = 0.01). The scores concerning the integrity of the sample were significantly higher with the Franseen needle (<i>p</i> = 0.02). Diagnostic sensitivity was higher with the Franseen needle (97.9 vs 88.5%, <i>p</i> = 0.02), whereas specificity was 100% with both needles. These findings were confirmed in subgroup analyses according to lesion location and final diagnosis. No adverse events were observed in both groups.</p> Conclusion <p>The 22G Franseen needle determines significantly higher adequacy and accuracy rates and the quality of the sample is higher as compared to the 20G forward bevel needle.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Comparison of Franseen Versus Forward Bevel Needle for EUS-Guided Fine-Needle Biopsy of Subepithelial Lesions: A Propensity Score Matching Analysis

  • 期刊论文

  • 发表日期：

    2026年3月17日

查看全文
  • Eyad Gadour,
  • Germana De Nucci,
  • Stefano Francesco Crinò,
  • Benedetto Mangiavillano,
  • Mattia Brigida,
  • Ioannis S. Papanikolaou,
  • Giuseppe Dell’Anna,
  • Abdulrahman Alfadda,
  • Gianfranco Donatelli,
  • Lucia Summa,
  • Bodour Raheem,
  • Elisa Stasi,
  • Armando Dell’Anna,
  • Antonio Facciorusso

摘要

Background

There is lack of direct comparison between different endoscopic ultrasound (EUS)-guided fine-needle biopsy (FNB) needles for tissue sampling of subepithelial lesions (SELs).

Aims

We aimed to compare Franseen vs forward bevel needle in patients with SELs.

Methods

Out of 483 patients undergoing endoscopic sampling of SELs, after propensity score matching two groups were compared: 145 undergoing EUS-FNB with 22G Franseen and 145 with 20G forward bevel needle. The primary outcome was diagnostic accuracy. Secondary outcomes were sample adequacy, quality of the sample, sensitivity, specificity, and adverse event rate.

Results

Sample adequacy and diagnostic accuracy rates were significantly higher with the Franseen needle (98.6 vs 89.6% and 96.5 vs 88.9%; p = 0.01). The scores concerning the integrity of the sample were significantly higher with the Franseen needle (p = 0.02). Diagnostic sensitivity was higher with the Franseen needle (97.9 vs 88.5%, p = 0.02), whereas specificity was 100% with both needles. These findings were confirmed in subgroup analyses according to lesion location and final diagnosis. No adverse events were observed in both groups.

Conclusion

The 22G Franseen needle determines significantly higher adequacy and accuracy rates and the quality of the sample is higher as compared to the 20G forward bevel needle.