Impact of Periampullary Diverticulum on ERCP Outcomes and Recurrence of Common Bile Duct Stones
摘要
This study was aimed to investigate the impact of periampullary diverticulum (PAD) on endoscopic retrograde cholangiopancreatography (ERCP) procedures and the recurrence of common bile duct stones (CBDS).
Methods830 CBDS cases with native papilla were finally enrolled in the study, including 239 cases with PAD (type I, type II, and type III). Procedures and complications of ERCP were compared between the two groups. The patients with successful stone removal were followed up every 6 months until December 31, 2023.
ResultsThe successful cannulation rate in the PAD group (96.7%) and type I PAD group (76.9%) was lower than that in the non-PAD group (99.2%). PAD was associated with a wider bile duct diameter, larger stone size, and a higher rate of cannulation with double guidewires, endoscopic sphincterotomy combined with endoscopic papillary balloon dilation and mechanical lithotripsy during the ERCP procedure. The incidence of complications did not differ between the two groups. Multivariate analysis revealed that PAD (OR = 3.265, 95%CI: 1.854–5.751) was an independent risk factor for the recurrence of CBDS.
ConclusionPAD, especially type I PAD, may impact ERCP cannulation success rates. Additionally, PAD increases the complexity of stone extraction and is associated with CBDS recurrence.