Purpose <p>Transdiagnostic psychological factors have been increasingly recognized as important mechanisms in the management of eating behaviors within obesity treatment. </p> Methods <p>The present study explored latent profiles of transdiagnostic factors (i.e., anxiety sensitivity, distress tolerance, emotion dysregulation, experiential avoidance, and mindfulness) and examined their associations with eating-related outcomes using the Bolck-Croon-Hagenaars (BCH) method among 163 adults with obesity (<i>M</i>_age = 31.54, <i>SD</i> = 10.67). </p> Results <p>Two distinct profiles emerged: a Maladaptive profile, characterized by heightened emotional reactivity and regulatory difficulties, and a Adaptive profile, characterized by greater psychological adaptability. Participants in the Maladaptive profile reported statistically significantly higher levels of emotional and external eating compared to those in the Adaptive profile, whereas no group differences were observed for restrained eating or food cravings. Sex did not predict profile membership, suggesting that these transdiagnostic patterns function similarly across sexes. </p> Conclusions <p>Overall, the findings highlight the combined influence of transdiagnostic factors on specific maladaptive eating behaviors and support the application of unified clinical interventions to enhance treatment outcomes.</p>