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Background <p>Hope is a cognitive-motivational resource relevant to psychotherapy, including cognitive behavioral therapy (CBT). Despite being proposed as a transdiagnostic mechanism of change, there is a lack of literature examining the contribution of hope to depression change during treatment. The present study addresses this literature gap by evaluating hope as a candidate mechanism of change during a transdiagnostic CBT.</p> Methods <p>Data were drawn from a CBT clinical trial including patients (<i>N</i> = 120) with depression and/or anxiety-related disorders who were repeatedly assessed during treatment. A series of multilevel models were conducted to examine (1) trajectories of hope and depression during treatment, (2) associations between changes in hope relative to baseline levels and depression symptoms, and (3) prospective associations between hope and depression symptoms.</p> Results <p>During treatment, hope significantly increased (<i>B</i> = 1.19, <i>β</i> = 0.04, <i>p</i> &lt; 0.001) and depression significantly decreased (<i>B</i> = -1.04, <i>β</i> = -0.04, <i>p</i> &lt; 0.001), increases in hope relative to baseline were significantly associated with lower depression (<i>B</i> = -0.54, <i>β</i> = -0.08, <i>p</i> &lt; 0.001), and higher prospective hope was significantly associated with lower subsequent depression (<i>B</i> = -0.16, <i>β</i> = -0.02, <i>p</i> = 0.014).</p> Conclusion <p>Alongside the broader hope literature, the present study provides preliminary evidence that hope may be a non-specific psychotherapeutic mechanism contributing to depression symptom change. These findings suggest that hope may play a supporting role in symptom change, complementing other central treatment processes principally driving reductions in depression.</p>

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Evaluating Hope as a Mechanism of Change in the Treatment of Depression

  • 期刊论文

  • 发表日期：

    2026年2月26日

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  • Daniel Teplow,
  • Laura Long,
  • Alexander Williams,
  • Julián Moreno-Villamizar,
  • Audrey Hey,
  • Madison Boschulte,
  • Daniella Spencer-Laitt,
  • Todd Farchione

摘要

Background

Hope is a cognitive-motivational resource relevant to psychotherapy, including cognitive behavioral therapy (CBT). Despite being proposed as a transdiagnostic mechanism of change, there is a lack of literature examining the contribution of hope to depression change during treatment. The present study addresses this literature gap by evaluating hope as a candidate mechanism of change during a transdiagnostic CBT.

Methods

Data were drawn from a CBT clinical trial including patients (N = 120) with depression and/or anxiety-related disorders who were repeatedly assessed during treatment. A series of multilevel models were conducted to examine (1) trajectories of hope and depression during treatment, (2) associations between changes in hope relative to baseline levels and depression symptoms, and (3) prospective associations between hope and depression symptoms.

Results

During treatment, hope significantly increased (B = 1.19, β = 0.04, p < 0.001) and depression significantly decreased (B = -1.04, β = -0.04, p < 0.001), increases in hope relative to baseline were significantly associated with lower depression (B = -0.54, β = -0.08, p < 0.001), and higher prospective hope was significantly associated with lower subsequent depression (B = -0.16, β = -0.02, p = 0.014).

Conclusion

Alongside the broader hope literature, the present study provides preliminary evidence that hope may be a non-specific psychotherapeutic mechanism contributing to depression symptom change. These findings suggest that hope may play a supporting role in symptom change, complementing other central treatment processes principally driving reductions in depression.