Scholarlink

<p>A new phenylpropanoid glycoside, named (7<i>E</i>)-1′-phenylethanol-6′-(3,5-dimethoxy-4-hydroxycinnamic acid) 3′′ ,4′′ -(11′′-carbonylfuran)-8′′ /11′′ -O-<i>β</i>-D-diglucopyranosylphenylpropanoid (<b>1</b>), and seven known phenylpropanoid glycosides (<b>2–8</b>) were isolated from <i>Vicatia thibetica</i> H. Boissieu for the first time. Their structures were elucidated by extensive spectroscopic methods (NMR, MS, UV, IR) and comparison with literature data. The anti-rheumatoid arthritis activities of these phenylpropanoid glycosides (<b>1–8</b>) were evaluated on a TNF-α induced MH7A human rheumatoid fibroblast-like synoviocyte model. Among them, compounds <b>1</b> and <b>2</b> exhibited important anti-rheumatoid arthritis activities.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Structurally Diverse Phenylpropanoid Glycosides with Anti-Rheumatoid Arthritis Activities from Vicatia thibetica

  • 期刊论文

  • 发表日期：

    2026年6月19日

查看全文
  • Jia-Zeng Guo,
  • Qin-Ge Ma,
  • Rong-Rui Wei

摘要

A new phenylpropanoid glycoside, named (7E)-1′-phenylethanol-6′-(3,5-dimethoxy-4-hydroxycinnamic acid) 3′′ ,4′′ -(11′′-carbonylfuran)-8′′ /11′′ -O-β-D-diglucopyranosylphenylpropanoid (1), and seven known phenylpropanoid glycosides (2–8) were isolated from Vicatia thibetica H. Boissieu for the first time. Their structures were elucidated by extensive spectroscopic methods (NMR, MS, UV, IR) and comparison with literature data. The anti-rheumatoid arthritis activities of these phenylpropanoid glycosides (1–8) were evaluated on a TNF-α induced MH7A human rheumatoid fibroblast-like synoviocyte model. Among them, compounds 1 and 2 exhibited important anti-rheumatoid arthritis activities.