Scholarlink

<p>With the aims of screening more antifungal metabolites, in this study, two new chromones (<b>1</b> and <b>2</b>), together with six known (<b>3–8</b>) analogs, were isolated from the cigar tobacco-derived endophytic fungi <i>Penicillium sclerotiorum</i>. Their structures were determined by means of HR-ESI-MS and extensive 1D and 2D NMR spectroscopic studies. The antifungal activity was tested for compounds <b>1–8</b> against Golovinomyces cichoracearum (the main pathogen of tobacco powdery mildew). The results revealed that compounds <b>1–8</b> demonstrated obvious anti-<i>G. cichoracearum</i> activity with inhibition rates within the range of 42.9% ± 4.4 to 65.2% ± 4.2 compared with the negative control. However, these rates are lower than that of the positive control (with an inhibition rate of 91.4% ± 4.9).</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Antifungal Activity of Chromones from a Cigar Tobacco-Derived Fungus Penicillium sclerotiorum

  • 期刊论文

  • 发表日期：

    2026年6月19日

查看全文
  • Si-Si Lin,
  • Dan He,
  • Jian-Xiong Zhao,
  • Bin Yang,
  • Yi-Wen Zhang,
  • Ben-Hui Li,
  • Hong-Hui Yang,
  • Yong-Jun Zhang,
  • Jin Wang,
  • Qiu-Fen Hu,
  • Jin Li,
  • Hou-Fa Zhou

摘要

With the aims of screening more antifungal metabolites, in this study, two new chromones (1 and 2), together with six known (3–8) analogs, were isolated from the cigar tobacco-derived endophytic fungi Penicillium sclerotiorum. Their structures were determined by means of HR-ESI-MS and extensive 1D and 2D NMR spectroscopic studies. The antifungal activity was tested for compounds 1–8 against Golovinomyces cichoracearum (the main pathogen of tobacco powdery mildew). The results revealed that compounds 1–8 demonstrated obvious anti-G. cichoracearum activity with inhibition rates within the range of 42.9% ± 4.4 to 65.2% ± 4.2 compared with the negative control. However, these rates are lower than that of the positive control (with an inhibition rate of 91.4% ± 4.9).