Scholarlink

<p>A new benzoxazinoid alkaloid, (2<i>R</i>)-2-<i>O</i>-(2′-methoxy-4′-carboxyphenyl)-2<i>H</i>-1,4-benzoxazin-3(4<i>H</i>)-one (<b>1</b>) was isolated from the extract of the whole plants of <i>Acanthus ilicifolius</i> var. <i>xiamenensis</i>, together with nine known compounds (<b>2</b>–<b>10</b>). The structure elucidations were based on analyses of spectroscopic and mass-spectrometric data, including 1D, 2D NMR, and HR-MS. All compounds were examined for their anti-inflammatory and cytotoxic activities. Compound <b>10</b> exhibited moderate cytotoxicity against the HeLa, HepG2, and KB cancer cell lines with IC<sub>50</sub> values ranging from 14.71 to 31.07 μM.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

A New Benzoxazinoid Alkaloid and Other Constituents from Acanthus ilicifolius var. xiamenensis

  • 期刊论文

  • 发表日期：

    2026年1月1日

查看全文
  • Xinhua Ma,
  • Nana Yang,
  • Yifan Zhang,
  • Shibiao Feng,
  • Jinhuang Shen,
  • Xiaohui Huang,
  • Yonghong Zhang

摘要

A new benzoxazinoid alkaloid, (2R)-2-O-(2′-methoxy-4′-carboxyphenyl)-2H-1,4-benzoxazin-3(4H)-one (1) was isolated from the extract of the whole plants of Acanthus ilicifolius var. xiamenensis, together with nine known compounds (2–10). The structure elucidations were based on analyses of spectroscopic and mass-spectrometric data, including 1D, 2D NMR, and HR-MS. All compounds were examined for their anti-inflammatory and cytotoxic activities. Compound 10 exhibited moderate cytotoxicity against the HeLa, HepG2, and KB cancer cell lines with IC50 values ranging from 14.71 to 31.07 μM.