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<p>A synthetic method for water-soluble conjugates of chlorin e<sub>6</sub> carboxyl derivatives with diacetone galactose is proposed. Studies of a primary assessment of the dark and photoinduced cytotoxicity showed that the obtained digalactose carboxychlorins were promising for further studies as potential photosensitizers for medical application.</p>

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Improved Synthetic Method for Water-Soluble Conjugates of a Chlorin e6 Carboxyl Derivative with Galactose – Potential Antitumor Photosensitizers

  • 期刊论文

  • 发表日期：

    2025年11月19日

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  • M. V. Mal’shakova,
  • Ya. I. Pylina,
  • D. V. Belykh

摘要

A synthetic method for water-soluble conjugates of chlorin e6 carboxyl derivatives with diacetone galactose is proposed. Studies of a primary assessment of the dark and photoinduced cytotoxicity showed that the obtained digalactose carboxychlorins were promising for further studies as potential photosensitizers for medical application.