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<p>Reactions of the alkaloid anabasine with benzene-, <i>p</i>-toluene-, <i>o</i>-methoxyphenyl-, 3,4-dimethylbenzene-, 2,4,6-trimethylbenzene-, and <i>m</i>-nitrophenylsulfonyl chlorides under relatively mild conditions afforded the corresponding <i>N</i>-arylsulfonyl anabasines in good yields. Results of <i>in vitro</i> antimicrobial tests showed that the compounds did not exhibit antibacterial effects against microorganism strains.</p>

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Synthesis of N-Arylsulfonyl Anabasines

  • 期刊论文

  • 发表日期：

    2025年9月18日

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  • M. I. Olimova,
  • A. R. Khurramov,
  • S. A. Sasmakov,
  • Kh. M. Bobakulov,
  • M. G. Levkovich,
  • Sh. S. Azimova,
  • B. Zh. Elmuradov

摘要

Reactions of the alkaloid anabasine with benzene-, p-toluene-, o-methoxyphenyl-, 3,4-dimethylbenzene-, 2,4,6-trimethylbenzene-, and m-nitrophenylsulfonyl chlorides under relatively mild conditions afforded the corresponding N-arylsulfonyl anabasines in good yields. Results of in vitro antimicrobial tests showed that the compounds did not exhibit antibacterial effects against microorganism strains.