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<p>A new alkaloid, dipiperamide H (<b>1</b>) and a known alkaloid, dipiperamide F (<b>2</b>), were isolated from the fruits of <i>Piper longum</i> L.. The chemical structures of these compounds were identified by extensive spectroscopic analyses. Furthermore, the molecular docking results indicate that compound <b>1</b> may act as an anti-inflammatory inhibitor.</p>

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A New Bisamide from Piper longum and its Molecular Docking Study with Akt

  • 期刊论文

  • 发表日期：

    2025年9月19日

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  • Zhengwen Wang,
  • Qiaoyu Yuan,
  • Wei Song,
  • Runlin Xiang,
  • Xinqiao Liu,
  • Zhiliang Ma

摘要

A new alkaloid, dipiperamide H (1) and a known alkaloid, dipiperamide F (2), were isolated from the fruits of Piper longum L.. The chemical structures of these compounds were identified by extensive spectroscopic analyses. Furthermore, the molecular docking results indicate that compound 1 may act as an anti-inflammatory inhibitor.