<p>A novel glycoside compound, 3-hydroxy-5-(<i>β</i>-D-glucopyranosyloxy)-hexanoic acid (<b>1</b>) has been isolated from the fruits of <i>Aronia melanocarpa</i> (Michx.) Britton, along with ten known compounds, vanillic acid 4-<i>O</i>-<i>β</i>-D-glucoside (<b>2</b>), (<i>R</i>)-4-<i>O-β</i>-D-glucopyranoyl-4-hydroxy-2-pentanone (<b>3</b>), (6<i>R</i>,9<i>R</i>)-roseoside (<b>4</b>), phloroacetophenone 2-<i>O</i>-glucoside (<b>5</b>), methyl (3<i>S,</i>5<i>S</i>)-5-hydroxy-3-(<i>β</i>-D-glucopyranosyloxy)hexanoate (<b>6</b>), <i>β</i>-D-glucopyranosyl benzoate (<b>7</b>), parasorboside (<b>8</b>), benzyl 6-<i>O-α</i>-L-arabinofuranosyl-<i>β</i>-D-glucoside (<b>9</b>), dihydrophasmaric acid 4′-<i>O-β</i>-D-glucopyranoside (<b>10</b>), and 4-<i>O-β</i>-D-glucopyranosyl-<i>cis-p</i>-coumaric acid (<b>11</b>). The structure of compound <b>1</b> was determined by NMR spectroscopic and MS analyses. Compounds <b>1–4</b> showed antibacterial activity against <i>Staphylococcus aureus</i> RN (4220).</p>

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A Novel Glycoside Compound and Antibacterial Constituents of the Fruits of Aronia melanocarpa

  • Jin Hui Ma,
  • Hong Lin Zhang,
  • En Ji Cui,
  • Chang Ji Zheng

摘要

A novel glycoside compound, 3-hydroxy-5-(β-D-glucopyranosyloxy)-hexanoic acid (1) has been isolated from the fruits of Aronia melanocarpa (Michx.) Britton, along with ten known compounds, vanillic acid 4-O-β-D-glucoside (2), (R)-4-O-β-D-glucopyranoyl-4-hydroxy-2-pentanone (3), (6R,9R)-roseoside (4), phloroacetophenone 2-O-glucoside (5), methyl (3S,5S)-5-hydroxy-3-(β-D-glucopyranosyloxy)hexanoate (6), β-D-glucopyranosyl benzoate (7), parasorboside (8), benzyl 6-O-α-L-arabinofuranosyl-β-D-glucoside (9), dihydrophasmaric acid 4′-O-β-D-glucopyranoside (10), and 4-O-β-D-glucopyranosyl-cis-p-coumaric acid (11). The structure of compound 1 was determined by NMR spectroscopic and MS analyses. Compounds 1–4 showed antibacterial activity against Staphylococcus aureus RN (4220).