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<p>In this research, 19 compounds were isolated from the leaves and branches of <i>Elaeagnus mollis</i> Diels. Of these, compound <b>1</b> was a new natural product, while compounds <b>2–11</b>, <b>13–19</b> were isolated for the first time from this genus. The isolated compounds were screened for hepatocyte proliferation and protective activity <i>in vitro</i>. Compounds <b>6–10</b>, <b>12</b>, and <b>18</b> exhibited both in vitro AML12 cell proliferation activity and protective activity against LPS-induced injury.</p>

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Chemical Constituents from the Branches and Leaves of Elaeagnus mollis and Screening of Anti-Liver Injury Activity

  • 期刊论文

  • 发表日期：

    2025年7月21日

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  • Ying Zhang,
  • Hongfeng Quan,
  • Jun Liu,
  • Lin Dong

摘要

In this research, 19 compounds were isolated from the leaves and branches of Elaeagnus mollis Diels. Of these, compound 1 was a new natural product, while compounds 2–11, 13–19 were isolated for the first time from this genus. The isolated compounds were screened for hepatocyte proliferation and protective activity in vitro. Compounds 6–10, 12, and 18 exhibited both in vitro AML12 cell proliferation activity and protective activity against LPS-induced injury.