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<p>A new alkaloid was isolated from <i>Portulaca oleracea</i> L., determined using spectroscopic methods, including UV, IR, 1D and 2D NMR, ultra-high-performance liquid chromatography coupled with electrospray ionization quadrupole time-of-flight mass spectrometry (UHPLC-ESI-Q-TOF/MS). The undescribed compound was named oleracrylimide F and was found to significantly reduce the interleukin-1<i>β</i> (IL-1<i>β</i>) and tumor necrosis factor-alpha (TNF-<i>α</i>) levels associated with inflammatory activity at 20 and 10 μM, respectively.</p>

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A New Alkaloid from Portulaca oleracea and its Bioactivity

  • 期刊论文

  • 发表日期：

    2025年5月21日

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  • Zheming Ying,
  • Kaiyun Jiang,
  • Chengyu Wang,
  • Hongzhe Zhang,
  • Yingdai Zhao,
  • Xiaoqian Zhang,
  • Xixiang Ying,
  • Yanling Ren

摘要

A new alkaloid was isolated from Portulaca oleracea L., determined using spectroscopic methods, including UV, IR, 1D and 2D NMR, ultra-high-performance liquid chromatography coupled with electrospray ionization quadrupole time-of-flight mass spectrometry (UHPLC-ESI-Q-TOF/MS). The undescribed compound was named oleracrylimide F and was found to significantly reduce the interleukin-1β (IL-1β) and tumor necrosis factor-alpha (TNF-α) levels associated with inflammatory activity at 20 and 10 μM, respectively.