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<p>Two new anthraquinone derivatives, named 1,3,6,8-tetrahydroxy-2-(methoxymethyl)anthracene-9,10-dione (<b>1</b>) and 1,3,6,8-tetrahydroxy-2-methylanthracene-9,10-dione (<b>2</b>), together with a known <i>γ</i>-pyrone derivative, kojic acid (<b>3</b>), were isolated from the mangrove rhizosphere soil-derived fungus <i>Aspergillus</i> sp. N4-8. The structures of compounds <b>1</b> and <b>2</b> were elucidated by combined spectroscopic methods including 1D and 2D NMR spectral data. Compounds <b>2</b> and <b>3</b> showed antibacterial activities.</p>

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Two New Anthraquinone Derivatives from the Marine-Derived Fungus Aspergillus sp. N4-8

  • 期刊论文

  • 发表日期：

    2025年3月24日

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  • Yi-Feng Huang,
  • Xia-Hao Zhu,
  • Li-Kui Zhang,
  • Li Shen,
  • Xiao-Jian Zhou,
  • Min Chen

摘要

Two new anthraquinone derivatives, named 1,3,6,8-tetrahydroxy-2-(methoxymethyl)anthracene-9,10-dione (1) and 1,3,6,8-tetrahydroxy-2-methylanthracene-9,10-dione (2), together with a known γ-pyrone derivative, kojic acid (3), were isolated from the mangrove rhizosphere soil-derived fungus Aspergillus sp. N4-8. The structures of compounds 1 and 2 were elucidated by combined spectroscopic methods including 1D and 2D NMR spectral data. Compounds 2 and 3 showed antibacterial activities.