Scholarlink

<p>The dual-functional nanostructures show great promise for biomedical applications, exhibiting selective cytotoxicity against cancer cells while also serving as a crucial component in textile screen-printing for smart materials. In this study, we successfully synthesized polyethylene glycol-hibiscus extract copper (II) oxide nanoparticles (PEG/HS/CuO NPs) using a simple one-step sonosynthesis method that leverages ultrasonic irradiation. Comprehensive characterization of the synthesized PEG/HS/CuO NPs was performed using transmission electron microscopy (TEM), X-ray diffraction (XRD), scanning electron microscopy (SEM) coupled with energy-dispersive X-ray (EDX) analysis, and Fourier-transform infrared spectroscopy (FTIR). The incorporation of PEG/HS/CuO NPs into guar gum photochromic solution (GP) caused a significant color change after 6 ± 1&#xa0;min of UV light exposure and resulted in visible coloration on cellulose-based textiles after screen printing, providing an alternative strategy for smart fabrics. Moreover, cytotoxicity experiments demonstrated the selective toxicity of green PEG/HS/CuO NPs against cancer cells. In this study, the human colon cancer cell line HCT116, breast cancer cell line MCF-7, and normal HUVEC cells were examined. PEG/HS/CuO NPs NPs induced apoptosis, cell cycle arrest, and down-regulation of CD44 antibody expression in MCF-7 cells, highlighting their potential as effective chemotherapy agents.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Dual-functionality of Hibiscus sabdariffa-CuO nanoparticles in chemotherapy and textile screen-printing on cellulose-based textiles

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年2月11日

查看全文
  • Elif Tüzün,
  • Ayşe Erol,
  • Ferdane Danışman Kalındemirtaş,
  • Fatih Özbaş,
  • Esra Sert,
  • Razium Ali Soomro,
  • Ayman Nafady,
  • Selcan Karakuş

摘要

The dual-functional nanostructures show great promise for biomedical applications, exhibiting selective cytotoxicity against cancer cells while also serving as a crucial component in textile screen-printing for smart materials. In this study, we successfully synthesized polyethylene glycol-hibiscus extract copper (II) oxide nanoparticles (PEG/HS/CuO NPs) using a simple one-step sonosynthesis method that leverages ultrasonic irradiation. Comprehensive characterization of the synthesized PEG/HS/CuO NPs was performed using transmission electron microscopy (TEM), X-ray diffraction (XRD), scanning electron microscopy (SEM) coupled with energy-dispersive X-ray (EDX) analysis, and Fourier-transform infrared spectroscopy (FTIR). The incorporation of PEG/HS/CuO NPs into guar gum photochromic solution (GP) caused a significant color change after 6 ± 1 min of UV light exposure and resulted in visible coloration on cellulose-based textiles after screen printing, providing an alternative strategy for smart fabrics. Moreover, cytotoxicity experiments demonstrated the selective toxicity of green PEG/HS/CuO NPs against cancer cells. In this study, the human colon cancer cell line HCT116, breast cancer cell line MCF-7, and normal HUVEC cells were examined. PEG/HS/CuO NPs NPs induced apoptosis, cell cycle arrest, and down-regulation of CD44 antibody expression in MCF-7 cells, highlighting their potential as effective chemotherapy agents.