Background <p>Adolescents’ perceptions of school safety are associated with mental health problems and elevated suicide risk. Drawing on Attachment Theory and Stress‑Buffering Theory, scholars have documented the importance of family and social relationships in influencing adolescents’ vulnerability to suicidal thoughts and behaviors.</p> Objective <p>This study tested whether parental attachment moderates the association between feeling unsafe at school and suicide attempts.</p> Method <p>Cross-sectional secondary analysis of the 2022 Florida Youth Substance Abuse Survey (<i>N</i> = 47,572; grades 6–12). Suicide attempts were self-reported for the past 12 months. Feeling unsafe was dichotomized (unsafe = 1), and parental attachment was captured through a four-item scale. Main effects were assessed using logistic regression with robust standard errors, and marginal effects were used to interpret the interaction.</p> Results <p>Feeling unsafe was associated with a 5% increase in the probability of a suicide attempt (<i>AME</i> = 0.05, <i>p</i> &lt; .001), while parental attachment was associated with a 4% decline in the outcome (<i>AME</i> = − 0.04, <i>p</i> &lt; .001). The interaction was consistent with a moderating effect, showing that the protective influence of attachment was proportionally weaker among students who felt unsafe.</p> Conclusions <p>Feeling unsafe in school and weak parental attachment each relate to greater suicide-attempt risk. Higher parental attachment is associated with lower risk for all students and narrows the gap between those who feel unsafe and those who feel safe. Strengthening both school safety and family bonds is associated with lower risk, although the cross-sectional design used here limits causal inferences.</p>