<p>The authors address a pressing problem in the mathematical modeling of glucose absorption from the human intestine under normal conditions, accounting for intestinal motility. To describe this process, modern physiology and medicine lack relevant clinical data and even methods for obtaining it. This problem is the first stage of more in-depth research into the function of intestinal glucose absorption, which has become particularly relevant due to the need to improve existing digital means of processing and recording relevant medical and diagnostic information and to develop new methods. The actual appearance of the function of intestinal glucose absorption under normal conditions is presented, which is consistent with both the known corresponding “secondary averaged normal clinical data” and all concepts in gastroenterology and physiology. The application of the results obtained in the study will undoubtedly improve the quality of diabetes mellitus (glucose homeostasis disorders) diagnosis and improve the automatic insulin pump control system.</p>

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Cybernetic Modeling of Intestinal Glucose Absorption Into Human Blood Under Normal Conditions

  • Y. Sokol,
  • S. Lapta,
  • O. Soloviova

摘要

The authors address a pressing problem in the mathematical modeling of glucose absorption from the human intestine under normal conditions, accounting for intestinal motility. To describe this process, modern physiology and medicine lack relevant clinical data and even methods for obtaining it. This problem is the first stage of more in-depth research into the function of intestinal glucose absorption, which has become particularly relevant due to the need to improve existing digital means of processing and recording relevant medical and diagnostic information and to develop new methods. The actual appearance of the function of intestinal glucose absorption under normal conditions is presented, which is consistent with both the known corresponding “secondary averaged normal clinical data” and all concepts in gastroenterology and physiology. The application of the results obtained in the study will undoubtedly improve the quality of diabetes mellitus (glucose homeostasis disorders) diagnosis and improve the automatic insulin pump control system.