Scholarlink

<p>We aimed to evaluate the capability of delayed enhancement cardiac computed tomography (DE-CT) for the qualitative and quantitative assessments of microvascular obstruction (MVO) in patients with ST-segment elevation myocardial infarction (STEMI) compared with late gadolinium enhancement magnetic resonance imaging (LGE-MRI).&#xa0;We compared DE-CT and LGE-MRI in patients with STEMI who underwent primary percutaneous coronary intervention (PCI) for a de novo lesion. Short-axis images from both modalities were used to measure hyper-enhanced areas (representing infarcted myocardium) and hypo-enhanced areas within the hyper-enhanced regions (representing MVO). These areas were summated for volumetric analyses.&#xa0;Twenty-two patients with STEMI underwent both DE-CT and LGE-MRI a median of eight days after successful primary PCI. MVO was identified in 16 (73%) patients on both DE-CT and LGE-MRI, with excellent agreement between modalities (κ = 0.88, <i>P</i> &lt; 0.001). Quantitatively, the median infarct volumes were 6475 (1850–14260) mm³ on DE-CT and 5756 (1709–14860) mm³ on LGE-MRI. The median MVO volumes were 706 (437–2737) mm³ on DE-CT and 647 (390–2650) mm³ on LGE-MRI. The correlations between DE-CT and LGE-MRI for infarcted myocardium volume (ρ = 0.976, <i>P</i> &lt; 0.0001) and MVO volume (ρ = 0.926, <i>P</i> &lt; 0.0001) were very strong.&#xa0;DE-CT is a viable alternative to LGE-MRI for both qualitative and quantitative assessments of infarcted myocardium and MVO in patients with STEMI.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Qualitative and quantitative evaluation of microvascular obstruction with delayed enhancement cardiac computed tomography in patients with ST-segment elevation myocardial infarction

  • 期刊论文

  • 发表日期：

    2025年12月1日

查看全文
  • Masahiro Takahata,
  • Yasutsugu Shiono,
  • Motoki Taniguchi,
  • Yoshinori Asae,
  • Akira Taruya,
  • Teruaki Wada,
  • Shingo Ota,
  • Yuichi Ozaki,
  • Manabu Kashiwagi,
  • Akio Kuroi,
  • Kazushi Takemoto,
  • Takashi Tanimoto,
  • Takashi Yamano,
  • Hironori Kitabata,
  • Atsushi Tanaka

摘要

We aimed to evaluate the capability of delayed enhancement cardiac computed tomography (DE-CT) for the qualitative and quantitative assessments of microvascular obstruction (MVO) in patients with ST-segment elevation myocardial infarction (STEMI) compared with late gadolinium enhancement magnetic resonance imaging (LGE-MRI). We compared DE-CT and LGE-MRI in patients with STEMI who underwent primary percutaneous coronary intervention (PCI) for a de novo lesion. Short-axis images from both modalities were used to measure hyper-enhanced areas (representing infarcted myocardium) and hypo-enhanced areas within the hyper-enhanced regions (representing MVO). These areas were summated for volumetric analyses. Twenty-two patients with STEMI underwent both DE-CT and LGE-MRI a median of eight days after successful primary PCI. MVO was identified in 16 (73%) patients on both DE-CT and LGE-MRI, with excellent agreement between modalities (κ = 0.88, P < 0.001). Quantitatively, the median infarct volumes were 6475 (1850–14260) mm³ on DE-CT and 5756 (1709–14860) mm³ on LGE-MRI. The median MVO volumes were 706 (437–2737) mm³ on DE-CT and 647 (390–2650) mm³ on LGE-MRI. The correlations between DE-CT and LGE-MRI for infarcted myocardium volume (ρ = 0.976, P < 0.0001) and MVO volume (ρ = 0.926, P < 0.0001) were very strong. DE-CT is a viable alternative to LGE-MRI for both qualitative and quantitative assessments of infarcted myocardium and MVO in patients with STEMI.