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Purpose <p>To evaluate the reproducibility of biventricular global longitudinal strain (GLS) assessment using cardiovascular magnetic resonance in a multicenter study of travelling volunteers.</p> Methods <p>Twenty travelling volunteers were prospectively scanned at four sites with same-vendor scanners at 3.0T (sites I, II, III) and 1.5T (site IV). Cine imaging in three long-axis views was performed using a segmented balanced steady-state free precession sequence with 30 cardiac phases except site II with 25 phases.</p> Results <p>Imaging and post-processing were carried out successfully for 18 volunteers in a core lab setting. Pairwise comparisons revealed significant differences in left ventricular (LV) GLS between sites I and II (<i>p</i> &lt; 0.001) and sites II and IV (<i>p</i> = 0.013), as well as in right ventricular (RV) GLS between sites I and IV (<i>p</i> = 0.027). RV GLS values were significantly higher at 3.0T (<i>p</i> = 0.024), whereas field strength had no significant impact on LV GLS (<i>p</i> = 0.153). Conversely, the use of 25 cardiac phases at site II was associated with significantly lower LV GLS values (<i>p</i> &lt; 0.001), while RV GLS remained unaffected (<i>p</i> = 0.825).</p> Conclusion <p>When applying feature tracking-based strain in a multicenter study, careful consideration should be given to the temporal resolution for LV longitudinal strain and to magnetic field strength for RV longitudinal strain.</p> Graphical Abstract <p></p>

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Reproducibility assessment of biventricular strain derived from Long-Axis feature tracking in travelling Volunteers - A study in the Berlin research network for cardiovascular magnetic resonance (BER-CMR)

  • 期刊论文

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  • 发表日期：

    2025年10月17日

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  • Clemens Ammann,
  • Ralf Felix Trauzeddel,
  • Maximilian Müller,
  • Leonhard Grassow,
  • Thomas Hadler,
  • Darian Viezzer,
  • Richard Hickstein,
  • Leonora Zange,
  • Edyta Blaszczyk,
  • Elias Daud,
  • Jeanette Schulz-Menger,
  • Jan Gröschel

摘要

Purpose

To evaluate the reproducibility of biventricular global longitudinal strain (GLS) assessment using cardiovascular magnetic resonance in a multicenter study of travelling volunteers.

Methods

Twenty travelling volunteers were prospectively scanned at four sites with same-vendor scanners at 3.0T (sites I, II, III) and 1.5T (site IV). Cine imaging in three long-axis views was performed using a segmented balanced steady-state free precession sequence with 30 cardiac phases except site II with 25 phases.

Results

Imaging and post-processing were carried out successfully for 18 volunteers in a core lab setting. Pairwise comparisons revealed significant differences in left ventricular (LV) GLS between sites I and II (p < 0.001) and sites II and IV (p = 0.013), as well as in right ventricular (RV) GLS between sites I and IV (p = 0.027). RV GLS values were significantly higher at 3.0T (p = 0.024), whereas field strength had no significant impact on LV GLS (p = 0.153). Conversely, the use of 25 cardiac phases at site II was associated with significantly lower LV GLS values (p < 0.001), while RV GLS remained unaffected (p = 0.825).

Conclusion

When applying feature tracking-based strain in a multicenter study, careful consideration should be given to the temporal resolution for LV longitudinal strain and to magnetic field strength for RV longitudinal strain.

Graphical Abstract