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Background <p>Accurate assessment of myocardial viability is crucial for guiding treatment decisions in patients with ischemic cardiomyopathy (ICM). Delayed gadolinium enhancement (DGE) is the current gold standard, but non-contrast methods like feature tracking (FT) analysis during dobutamine stress are emerging. This work evaluates the efficiency of myocardial viability assessment using cardiac magnetic resonance feature tracking (CMR-FT) during stress by low-dose dobutamine.</p> Methods <p>This retrospective case-control study enrolled 50 ICM patients who underwent CMR at rest and during low-dose dobutamine stress. FT analysis was performed to assess circumferential, radial, and longitudinal strain at both rest and stress. DGE was used as reference to determine viability.</p> Results <p>Significant strain improvement with dobutamine was observed in segments deemed viable by DGE, while non-viable segments showed no improvement.</p> Conclusion <p>CMR-FT during low-dose dobutamine stress shows promise as non-contrast method for assessing myocardial viability in ICM patients, providing a potential alternative to DGE.</p>

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Assessment of myocardial viability using cardiac magnetic resonance feature tracking at rest and during low-dose dobutamine stress: a comparison with delayed gadolinium enhancement

  • 期刊论文

  • 发表日期：

    2025年9月29日

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  • Nisreen A. A. Mohammed,
  • Abdulrahman Hamdan,
  • Gehan S. Seifeldein,
  • Soha Romeih,
  • Mahmoud Shaaban,
  • Wesam Elmozy

摘要

Background

Accurate assessment of myocardial viability is crucial for guiding treatment decisions in patients with ischemic cardiomyopathy (ICM). Delayed gadolinium enhancement (DGE) is the current gold standard, but non-contrast methods like feature tracking (FT) analysis during dobutamine stress are emerging. This work evaluates the efficiency of myocardial viability assessment using cardiac magnetic resonance feature tracking (CMR-FT) during stress by low-dose dobutamine.

Methods

This retrospective case-control study enrolled 50 ICM patients who underwent CMR at rest and during low-dose dobutamine stress. FT analysis was performed to assess circumferential, radial, and longitudinal strain at both rest and stress. DGE was used as reference to determine viability.

Results

Significant strain improvement with dobutamine was observed in segments deemed viable by DGE, while non-viable segments showed no improvement.

Conclusion

CMR-FT during low-dose dobutamine stress shows promise as non-contrast method for assessing myocardial viability in ICM patients, providing a potential alternative to DGE.