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<p>Takayasu arteritis (TA) is a chronic, granulomatous vasculitis which primarily affects large elastic arteries including the aorta and its major branches, leading to stenosis, occlusion, and aneurysm formation [de Souza et al. in Journal of Autoimmunity 48:79–83, 2014; Pelletier-Galarneau and Ruddy in Current Cardiology Reports 21(5), 2019,&#xa0;<a href="https://doi.org/10.1007/s11886-019-1122-z">https://doi.org/10.1007/s11886-019-1122-z</a>]. Additional sequelae include heart failure secondary to hypertension, aortic regurgitation, and coronary artery involvement [Comarmond et al. in Circulation 136(12):1114–1122, 2017]. We describe the case of a young woman with progressive TA highlighting the role of fluorodeoxyglucose positron emission tomography-computed tomography (FDG-PET CT) in evaluating active inflammation. While FDG-PET CT can also be used to monitor response to treatment, this case demonstrates the utility of FDG-PET CT in evaluating active arteritis, allowing radiologists to help the clinician in guiding appropriate management.</p>

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NASCI case of the month: “the role of FDG PET-CT in detecting active Takayasu arteritis”

  • 期刊论文

  • 发表日期：

    2025年7月19日

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  • Unie Háng,
  • Morgan Sly,
  • Dharshan Vummidi

摘要

Takayasu arteritis (TA) is a chronic, granulomatous vasculitis which primarily affects large elastic arteries including the aorta and its major branches, leading to stenosis, occlusion, and aneurysm formation [de Souza et al. in Journal of Autoimmunity 48:79–83, 2014; Pelletier-Galarneau and Ruddy in Current Cardiology Reports 21(5), 2019, https://doi.org/10.1007/s11886-019-1122-z]. Additional sequelae include heart failure secondary to hypertension, aortic regurgitation, and coronary artery involvement [Comarmond et al. in Circulation 136(12):1114–1122, 2017]. We describe the case of a young woman with progressive TA highlighting the role of fluorodeoxyglucose positron emission tomography-computed tomography (FDG-PET CT) in evaluating active inflammation. While FDG-PET CT can also be used to monitor response to treatment, this case demonstrates the utility of FDG-PET CT in evaluating active arteritis, allowing radiologists to help the clinician in guiding appropriate management.