<p>Currently, reservoir evolution simulation experiments under normal pressure conditions are quite common, while reservoir evolution simulation experiments under abnormally high pressure conditions are relatively rare. In order to further clarify the quantitative impact of high temperature and overpressure on the evolution of reservoir pores, the reservoirs in the eastern area of Yinggehai Basin were taken as the research object. Physical simulation experiments were applied to explore the influence of overpressure on the evolution of reservoir pores under the background of sedimentation, diagenesis, and temperature and pressure, and to clarify the main controlling factors of high-quality reservoirs in the eastern area. The experimental results show that: Under normal pressure and overpressure conditions, there is a negative correlation between burial depth and porosity, that is, the porosity gradually decreases with increasing burial depth; Overpressure has a protective effect on porosity, and in this experiment, the maximum protection of porosity by overpressure can reach 12.54% The compaction effect causes microcracks in the sample particles, and as the temperature and pressure conditions increase, the number of microcracks gradually increases. The conclusion is that: Overpressure is conducive to the formation of microcracks and has a good protective effect on porosity. Compared with the normal pressure group, the overpressure group has more microcracks and higher porosity. The protection of primary pores by overpressure is the most constructive effect in reservoirs under high-temperature overpressure background, and the stronger the overpressure, the greater the protective effect on pores.</p>