<p>This study evaluates the seismic performance of prefabricated reinforced concrete industrial structures following the February 6, 2023, Kahramanmaraş earthquakes. A total of 595 industrial structures located in Organized Industrial Zones in Kahramanmaraş province were evaluated in terms of post-earthquake damage data officially obtained from the Republic of Türkiye Ministry of Environment, Urbanization and Climate Change. The results indicate that approximately 20% of the industrial structure was severely damaged or collapsed. In the assessments conducted by local municipalities on 96 incomplete prefabricated industrial structures, approximately 13% were found to have sustained heavy damage. The field observations showed that the damage was largely due to inadequacies in the design and manufacturing processes, incompatibilities between project design and field applications, and deficiencies in critical joint details. Especially, the hinged connections at the column-to-rafter beam and column-to-foundation joints are one of the most sensitive points against earthquakes and have played a decisive role in structural damage. The changes in natural vibration periods were assessed through numerical analyses performed in SAP2000 for nine moderately damaged prefabricated industrial buildings examined under three different scenarios: undamaged, damaged, and retrofitted conditions. Findings strongly advocate for revisions in seismic code provisions, strengthened quality control in construction practices, and the adoption of performance-based design approaches for prefabricated systems. This study provides critical empirical evidence to inform future seismic design guidelines and enhance the resilience of industrial facilities against large-magnitude earthquakes.</p>