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<p>A numerical experiment was conducted to determine the spectral sensitivity and selectivity of the cellular components of the utricle and saccule of a laboratory animal (rat) to a periodic electrical stimulation. Equivalent electrical circuit of otolith replacement was used. Its parameters were determined from the anatomical structure and from the measured specific characteristics of cellular elements taking into account the changing ionic conductivity. It was found that the frequency dependence of the impedance and the spectral sensitivity of the cell elements for the utricle and saccule have a resonant nature. The obtained data about the mechanisms of electrical stimulation of hair cells, their spectral sensitivity, and frequency selectivity can serve as the basis for choosing the optimal mode of electrical stimulation in a vestibular implant.</p>

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Modeling of Frequency Dependence of Selectivity and Sensitivity of Mammalian Otolith Membranes during Electrical Stimulation of the Vestibular Nerves

  • 期刊论文

  • 发表日期：

    2025年4月1日

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  • V. V. Udut,
  • V. P. Demkin,
  • S. V. Melnichuk,
  • T. V. Rudenko,
  • M. V. Svetlik,
  • M. D. Akinina,
  • O. V. Demkin,
  • L. V. Smaglii,
  • V. M. Alifirova,
  • O. V. Grebenuk

摘要

A numerical experiment was conducted to determine the spectral sensitivity and selectivity of the cellular components of the utricle and saccule of a laboratory animal (rat) to a periodic electrical stimulation. Equivalent electrical circuit of otolith replacement was used. Its parameters were determined from the anatomical structure and from the measured specific characteristics of cellular elements taking into account the changing ionic conductivity. It was found that the frequency dependence of the impedance and the spectral sensitivity of the cell elements for the utricle and saccule have a resonant nature. The obtained data about the mechanisms of electrical stimulation of hair cells, their spectral sensitivity, and frequency selectivity can serve as the basis for choosing the optimal mode of electrical stimulation in a vestibular implant.