Scholarlink

<p>The clinical significance of the total area of mitochondria index in the right atrial appendage cardiomyocytes was evaluated. The index was calculated as the ratio of the total area of interfibrillar mitochondria to the area of the interfibrillar space (S<sub>MT</sub>/S<sub>IFS</sub>). A total of 39 micrographs of cardiomyocytes from 12 patients with heart failure (left ventricular ejection fraction LV EF&lt;50%) and with obstructive multivessel coronary artery disease were analyzed. The results of the electron microscopy study were compared with the main echocardiography parameters and the functional status of the patients. It was found that the computed S<sub>MT</sub>/S<sub>IFS</sub> index was associated with general functional status according to the 6-min walk and cardiopulmonary exercise tests.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Total Area of Interfibrillar Mitochondria in the Right Atrial Appendage Cardiomyocytes as an Index of the Functional State of the Cardiovascular System in Chronic Heart Failure

  • 期刊论文

  • 发表日期：

    2025年2月1日

查看全文
  • E. A. Kuzheleva,
  • A. A. Garganeeva,
  • O. V. Tukish,
  • K. N. Vitt,
  • S. L. Andreev,
  • E. E. Syromyatnikova,
  • E. A. Vladimirova

摘要

The clinical significance of the total area of mitochondria index in the right atrial appendage cardiomyocytes was evaluated. The index was calculated as the ratio of the total area of interfibrillar mitochondria to the area of the interfibrillar space (SMT/SIFS). A total of 39 micrographs of cardiomyocytes from 12 patients with heart failure (left ventricular ejection fraction LV EF<50%) and with obstructive multivessel coronary artery disease were analyzed. The results of the electron microscopy study were compared with the main echocardiography parameters and the functional status of the patients. It was found that the computed SMT/SIFS index was associated with general functional status according to the 6-min walk and cardiopulmonary exercise tests.