<p>In recent years, technological innovations have changed aquaculture by promoting sustainability and increasing its production efficiency. Among the key technologies that are transforming aquaculture are integrated multi-trophic aquaculture (IMTA), aquaponics and aqua geoponics, aqua mimicry, biofloc technology, microalgae applications, genetic improvement and selective breeding, artificial intelligence (AI), automated sensing technology, blockchain technology, and satellite monitoring. These novelties are planned to avoid disease outbreaks, increase yields, and promote ecologically friendly aquaculture methods, as well as increased yield. By focusing on these advanced technologies in sustainable aquaculture, this review highlights their vital role in enhancing productivity and promoting long-term environmental resilience. Evidence from the reviewed studies shows that IMTA and aquaponics enhance nutrient recycling and reduce environmental footprints, while aqua mimicry and biofloc systems improve water quality, boost feed efficiency, and lower disease risks. Microalgae supplementation enhances growth, immunity, and bioremediation, whereas selective breeding and genetic improvements significantly increase growth rates, feed conversion efficiency, and resilience to stressors. AI and sensing technologies allow real-time monitoring, predictive feeding, and early disease detection, cutting operational costs. Blockchain ensures transparency and traceability in supply chains, while satellite monitoring supports site selection and environmental risk assessment. Collectively, these innovations demonstrate a measurable improvement in yields, reduced ecological impacts, and higher profitability across diverse aquaculture systems. This review underscores that integrating advanced biotechnological and digital tools is essential for achieving sustainable, resilient, and economically viable aquaculture, offering aqua culturists and farmers practical pathways to enhance productivity and sustainability.</p>