Scholarlink

<p>In the 21 Global Plan priority countries in SSA, including Ethiopia, 110,000 children are newly infected with HIV annually. Most pediatric infections occur during breastfeeding through vertical transmission, with a transmission risk of 15-45%, which can be reduced to 5% with effective interventions. Despite declining MTCT rates in Ethiopia, recent studies still report significant infection rates in infants. This study aims to assess HIV status and its associated factors among children born to women living with HIV on ART. An institution-based cross-sectional study was conducted in three randomly selected public hospitals in the Gambela region. A sample size of 250 was initially calculated using EpiInfo, applying the single population proportion formula and accounting for a 10% nonresponse rate. Of these, 241 participants were successfully enrolled. Sample distribution was proportionally allocated based on ART clinic attendance. Data were collected through interviews, entered into EpiData version 4.6.0.2, and analyzed using SPSS version 26. Logistic regression analysis was performed to identify factors associated with HIV status, with statistical significance set at <i>p</i> &lt; .05 and 95% confidence intervals reported. This study revealed that 7% of children born to women living with HIV were also infected with HIV. Mothers aged 30–39 years (AOR = 8.7), place of residence (rural) (AOR = 6.7), positive results for syphilis (AOR = 19.6), and unplanned pregnancies (AOR = 10.4) were significantly associated with HIV infection of children. Mother to child transmission remains a challenge in Gambela, Ethiopia. Child infection was associated with older maternal age, rural residence, unplanned pregnancy and maternal syphilis. Strengthening PMTCT interventions, integrating syphilis/HIV care, and expanding family planning and rural outreach are needed.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

HIV Status and Its Associated Factors of Children Born to HIV-Positive Mothers on ART at Gambella Public Hospitals, South West Ethiopia, 2024

  • 期刊论文

  • 发表日期：

    2026年1月9日

查看全文
  • Abel Felege,
  • Daniel Girma,
  • Haymanot Berihun

摘要

In the 21 Global Plan priority countries in SSA, including Ethiopia, 110,000 children are newly infected with HIV annually. Most pediatric infections occur during breastfeeding through vertical transmission, with a transmission risk of 15-45%, which can be reduced to 5% with effective interventions. Despite declining MTCT rates in Ethiopia, recent studies still report significant infection rates in infants. This study aims to assess HIV status and its associated factors among children born to women living with HIV on ART. An institution-based cross-sectional study was conducted in three randomly selected public hospitals in the Gambela region. A sample size of 250 was initially calculated using EpiInfo, applying the single population proportion formula and accounting for a 10% nonresponse rate. Of these, 241 participants were successfully enrolled. Sample distribution was proportionally allocated based on ART clinic attendance. Data were collected through interviews, entered into EpiData version 4.6.0.2, and analyzed using SPSS version 26. Logistic regression analysis was performed to identify factors associated with HIV status, with statistical significance set at p < .05 and 95% confidence intervals reported. This study revealed that 7% of children born to women living with HIV were also infected with HIV. Mothers aged 30–39 years (AOR = 8.7), place of residence (rural) (AOR = 6.7), positive results for syphilis (AOR = 19.6), and unplanned pregnancies (AOR = 10.4) were significantly associated with HIV infection of children. Mother to child transmission remains a challenge in Gambela, Ethiopia. Child infection was associated with older maternal age, rural residence, unplanned pregnancy and maternal syphilis. Strengthening PMTCT interventions, integrating syphilis/HIV care, and expanding family planning and rural outreach are needed.